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The Impact of Severe Obesity, Inflammation, and Insulin Resistance on Mortality and Cancer Risk, and the Role of Healthy Lifestyles in Modification


A recent study published in the Cancer Journal Clin showcases the global cancer statistics for 2020, providing estimates of the incidence and mortality rates for 36 types of cancers across 185 countries. The study highlights the significant impact of obesity on cancer risk and mortality, with multiple research articles emphasizing the link between body mass index (BMI), inflammation, and chronic diseases like cancer.

Research from various sources, including the Lancet, JAMA, and the New England Journal of Medicine, has consistently shown a correlation between higher BMI levels and increased risk of developing various types of cancer. Studies have also explored other factors such as inflammation, insulin resistance, and lifestyle choices in relation to cancer incidence and mortality.

The UK Biobank, a valuable resource for cancer research, has been instrumental in studying the impact of lifestyle, genetic factors, and chronic diseases on cancer risk. Recent studies have also investigated the role of systemic immune inflammation in predicting mortality outcomes in conditions like chronic kidney disease and hypertension.

Overall, the findings suggest that maintaining a healthy lifestyle, including a balanced diet, regular physical activity, and managing chronic conditions like diabetes, can significantly reduce the risk of developing cancer and improve survival outcomes. This research reinforces the importance of preventive measures and early detection in combating the global burden of cancer.

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Photo credit www.nature.com

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